| 課程大綱 | If the cervical status is unfavorable, a ripening process is generally employed prior to induction to shorten the duration of induction and maximize the possibility of vaginal delivery.The two major techniques for cervical ripening are mechanical interventions, such as insertion of balloon catheters or, less commonly, hygroscopic cervical dilators, and application of pharmacologic agents, such as prostaglandins.Choice of cervical ripening agent — The ideal methods for cervical ripening and labor induction have yet to be identified. Clinical studies of human parturition are hindered by a lack of understanding of the physiologic events that initiate and sustain labor. There is wide biologic variation among pregnant women in the progress of normal labor and iatrogenic variation in the management of labor and labor induction; this makes the investigation of new uterotonic agents difficult. Although data from randomized trials comparing different cervical ripening approaches are available, there are insufficient comparative data to determine which of several methods (type, dose, inpatient/outpatient) is the most effective and offers the best safety profile. Variation in indications for induction, parity, and gestational age at induction, as well as other demographic features, undoubtedly affects clinical results. |